
Tissue similar to the uterine lining grows outside the uterus (on ovaries, fallopian tubes, pelvic peritoneum, bowel, bladder). This tissue responds to hormones, causing inflammation, scarring, and pain.
Painful periods, deep pelvic pain with sex, chronic pelvic pain, painful bowel movements/urination (especially during periods), bloating, fatigue, and sometimes infertility.
Suspected clinically from symptoms and exam; transvaginal ultrasound can identify endometriomas
(ovarian cysts). Laparoscopy is the gold standard when diagnosis is uncertain or when surgery is planned.
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Pain control: NSAIDs.
Hormonal suppression: continuous combined pills, progestins (including **LNG-IUS** and dienogest), GnRH analogs/antagonists with add-back therapy.
Fertility-focused care: options range from ovulation induction/IUI to IVF depending on age, ovarian reserve, severity, and other factors.
Surgery: laparoscopic excision/ablation of implants and lysis of adhesions for pain relief or to improve fertility; endometrioma cystectomy when appropriate.
Multidisciplinary support (pelvic floor therapy, pain specialists, nutrition, mental health) often improves quality of life. Recurrence is possible; long-term medical suppression reduces relapse risk for many.
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Disease behavior: lesions can be superficial, ovarian (endometriomas), or deeply infiltrating (affecting ligaments, bowel, bladder).
Pain mechanisms: inflammation, nerve growth in lesions, and adhesions.
Long-term plan: since endometriosis is chronic for many, ongoing hormonal suppression after surgery lowers recurrence; fertility decisions guide whether to favor medical vs. surgical strategies at each stage.
Bowel/bladder symptoms: rectal bleeding or cyclical urinary symptoms warrant targeted imaging and a multidisciplinary surgical plan when needed.
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